Saint Mary's Hall is located in Northeast San Antonio near Loop 410 and Starcrest Drive just minutes from the San Antonio Airport.

From West San Antonio and 281 Interchange:
Take Loop 410 East passing the airport. After only 1-2 miles, exit Starcrest and turn left going over the freeway. Continue straight on Starcrest until the road dead ends at the school's main entrance.

From East San Antonio and New Braunfels:
Take I-35 Sout toward San Antonio and take Loop 410W. Almost immediately, you will exit Starcrest. (If you see the exit for the airport, you have gone too far). At the light, turn right onto Starcrest Drive. Continue straight on Starcrest until the road dead ends at the school's main entrance.